CLN Wiki · Nutrition
Borage Oil
Borage oil provides the rare anti-inflammatory Omega-6 needed to balance neural immune responses.
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Definition
Term
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Borage Oil — oil extracted from seeds of Borago officinalis
(starflower)
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richest plant source of GLA (gamma-linolenic acid):
20–26%
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cognitive relevance: anti-inflammatory support for brain function
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Key Compound: GLA
Mechanism
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GLA = gamma-linolenic acid (omega-6 fatty acid)
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converts to DGLA → produces anti-inflammatory prostaglandins (PGE1)
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modulates neuroinflammation — chronic inflammation impairs cognition
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unlike most omega-6, GLA is ANTI-inflammatory (unique metabolic pathway)
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Cognitive Relevance
Impact
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neuroinflammation linked to: brain fog, poor concentration, memory decline
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GLA → DGLA → PGE1 pathway reduces neuroinflammation
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may support myelin sheath integrity (nerve signal speed)
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synergistic with omega-3: GLA + EPA/DHA = balanced
inflammation control
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Dosage & Safety
Practical
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typical: 1000–1300mg borage oil / day (= 200–300mg GLA)
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forms: soft capsules, liquid oil
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must be cold-pressed (heat destroys GLA)
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choose PA-free (pyrrolizidine alkaloid free) — liver safety
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not a substitute for omega-3 — complementary, not replacement